Our Breakthrough Findings
In the Palm of Your Hand

Rooted in 25+ years of in-depth scientific research, we are unleashing a new approach to address the widespread Type 2 diabetes crisis by redefining the liver's role as central in understanding, preventing, managing, and ultimately reversing Type 2 diabetes and metabolic syndrome.

Learn More

With a passionate commitment to leverage rigorous science for the benefit of human health, the SciMar team has focused its energy on defining and unleashing this new paradigm for the prevention, detection, management, and, ultimately, the reversal of Type 2 diabetes.

Our success in the lab has allowed us to develop powerful, revolutionary products to support your best efforts to get healthy and stay healthy. Our goal is to change global health for the better. We’d like to start with you.

What is Metabolic Syndrome?

Metabolic syndrome is a cluster of conditions that occur together, increasing your risk of heart disease, stroke, and Type 2 diabetes. These conditions include increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels.

SOURCE: Mayo Clinic (https://www.mayoclinic.org/diseases-conditions/metabolic-syndrome/symptoms-causes/syc-20351916)

What We Found

In 1996, Dr. W. Wayne Lautt announced that he had discovered a hormone produced by the liver. He observed the impact of this hormone on glucose uptake and later named the hormone hepatalin***

In young, healthy humans, hepatalin does two-thirds of the heavy lifting of reducing elevated blood sugar. As we age and ingest more refined sugar, we destroy the production of hepatalin in our bodies.

We need the right balance of hepatalin and insulin to stay healthy.

Nutrient Partitioning

When we eat a meal, our bodies absorb energy from food as glucose, which is a form of sugar. Some of that glucose is used immediately as energy. What happens to the excess glucose helps to determine our well-being. Some of the glucose is stored in our muscle cells as “glycogen”; some of it is stored in fat cells as "triglycerides". If our nutrient partitioning is optimal, our muscles take most of the glucose. If our nutrient partitioning is poor, more glucose gets stored as fat.

After extensive study, it became clear to Dr. W. Wayne Lautt that hepatalin causes excess glucose to be taken up by muscle. Once the liver cannot sufficiently produce hepatalin, our pancreas creates additional insulin, causing nutrient energy to be partitioned into fat.

Feeding Signals for HISS Release

In the academic literature, hepatalin is known as hepatic insulin-sensitizing substance (the “HISS” hormone). “HISS” and “hepatalin” are interchangeable terms.

Feeding results in an increase of hepatic glutathione (GSH) and a parasympathetic signal to the liver that acts, via acetylcholine (ACh), on muscarinic receptors to activate nitric oxide (NO) release. Both of these signals are permissive and both are needed in order for insulin to cause the release of HISS.

The blockade of any portion of these pathways leads to blockade of HISS release and a state of HISS-dependent insulin resistance. HISS release is physiologically regulated to be absent in the fasted state, but when HISS release is not activated by feeding, its absence is suggested to account for postprandial hyperglycemia, hyperinsulinemia, hyperlipidemia, and increased oxidative stress.

Chronic lack of HISS action results in a progressive and predictable series of homeostatic dysfunctions typical of obesity and Type 2 diabetes.

Lautt, Wayne & Wang, Hui. (2015). Obesity as an Early Symptom of the AMIS Syndrome. Journal of clinical medicine. 3. 1178-98. 10.3390/jcm3041178.

"Our bodies need a certain amount of insulin, but without a proper balance between hepatalin and insulin, we move toward Type 2 diabetes and metabolic syndrome with the potential consequences of stroke, heart disease, and death."

Dr. W. Wayne Lautt

Prof. Emeritus at the University of Manitoba, Founder, Chief Scientific Officer, SciMar Ltd

Vitamin C + Vitamin E + SAMe = SciMar NuPa Daily

Through many years of research, Dr. W. Wayne Lautt and his team have developed a powerful combination of compounds that support healthy liver function and strengthen your body’s ability to metabolize nutrients
effectively—key factors in the preservation of metabolic health.

While each ingredient will benefit your overall health and wellness, SciMar NuPa Daily's delayed-release formulation delivers all of the active ingredients at the right moment, thereby working to support your metabolism at the cellular level. By starting your day with SciMar NuPa Daily, you are supporting your best efforts to get healthy and stay healthy.

Vitamin C 1000 MG

Helps to maintain healthy bones, cartilage, teeth, and gums. Helps with wound healing and connective tissue formation. Source of an antioxidant for the maintenance of good health. An antioxidant that helps protect cells from the oxidative damage caused by free radicals. Aids in collagen formation. Supports immune function. Maintains the body's ability to metabolize nutrients effectively.

Vitamin E 330 MG

Helps to support the maintenance of good health. Helps to fight against the oxidative damage caused by free radicals.

S-adenosyl-L-methionine 400 MG

Helps to support a healthy mood balance. Helps to support a healthy liver function.

We use high-quality raw materials, ensuring maximum bioavailability.

A daily dose of SciMar NuPa Daily comprises four capsules, taken together at the beginning of the day on an empty stomach. For your convenience, SciMar NuPa Daily is packaged in weekly strips. Each strip is divided into seven packets containing your SciMar NuPa Daily supplements; each packet labeled with the day of the week.

SciMar NuPa Daily
Helps to Maintain Your…

Metabolism

Supports your best efforts at achieving metabolic health.

SciMar NuPa Daily was developed by measuring the effects of various compounds in our metabolism at a cellular level. Our scientifically formulated antioxidant is designed to support the proper metabolism of nutrients while helping you fight the progression of metabolic syndrome.

Immunity

Supports the proper functioning of your immune system.

Vitamin C is one of the most powerful immune system boosters of all. To effectively reap its rewards, vitamin C must be taken daily, as our bodies do not create or store it. Vitamin E is also an effective antioxidant.

Mood Balance

Supports a healthy well-being.

SciMar NuPa Daily helps promote emotional balance by restoring a healthy level of SAMe. As SAMe production decreases as we age, enriching our bodies with this natural compound clinically proven to boost our mood is a major step toward a revitalized self.